A Bioinformatic Studies of Moringaoleifera L. as A Gout Drug

Abstract

Moringaoleifera Lam. (MO) is a plant that has been widely known for its usefulness by the people of Indonesia which is called Moringa. MO belongs to the Moringaceae family. Moringa plant is a local food material that has the potential to be developed to cure uric acid naturally, because the moringa leaves contain active compounds, namely phlovonoids and alkaloids which can prevent the formation of uric acid, besides that Moringa leaves can also be used as anti-inflammatory (inflammation) and analgesic (pain reliever). Gout is a disease of purine metabolic waste products that come from the food we eat. This disorder is associated with the accumulation of urosal crystals monosodium monohydrate and in the later stages of degeneration of joint cartilage, the incidence of gout is 1-2%, especially occurs at the age of 30-40 years and 20 times more often in men than in women. The method used is a computational study using various bioinformatics applications. From the research results, it was found that the active compound in Moringa leaves is effective as a uric acid drug.

Keywords: Alkaloids; Curcuma; Moringaoleifera lam. (MO); Phlovonoids; Uric acid