COMPUTATIONAL BIOINFORMATICS STUDY OF NONI TO LOWER CHOLESTEROL LEVELS (MORINDA CITRIFOLIA)

Abstract

Increased cholesterol levels or also known as hypercholesterolemia is one of the risk factors for coronary heart disease. A person can be categorized as having hypercholesterolemia if the cholesterol level is declared high if in adults the cholesterol value reaches> 240 mg/dl while in children and adolescents the total cholesterol value reaches 200 mg/dl or more has been declared high. To reduce hypercholeterolemia or cholesterol levels in the blood, it can be done using traditional medicine, one of which is noni fruit. Noni fruit (Morinda citrifolia) can reduce total blood cholesterol, LDL, triglycerides and increase HDL and can improve the histology structure of the aortic vessels (thickening of the tunica media) in mice given a high-fat diet.